The Detroit Lions will play without two high draft picks in rookie cornerbacks Terrion Arnold and Ennis Rakestraw Jr. while possibly getting back veteran Emmanuel Moseley against the host Indianapolis Colts on Sunday.

Arnold was downgraded Saturday from questionable to out because of a groin injury. He was limited at practice on Thursday and participated in a full practice on Friday.

The Lions drafted Arnold with the 24th overall pick of the 2024 NFL Draft out of Alabama. Arnold, 21, has started all 10 games and has 38 tackles and six passes defended.

Rakestraw (hamstring) was placed on injured reserve after not practicing all week. He already had been ruled out for Sunday’s game.

Detroit picked Rakestraw in the second round (61st overall) out of Missouri. He has played in eight games and has six tackles. Rakestraw, 22, has played on 46 defensive snaps (8 percent) and 95 special teams snaps (42 percent).

Moseley had full practice sessions all week and was activated from injured reserve on Saturday but was listed as questionable for Sunday.

The 28-year-old is in his second season with Detroit and appeared in one game last season before going on IR in October 2023. He was placed on IR on Aug. 27 with a designation to return.

Moseley played from 2018-22 for the San Francisco 49ers and had 162 tackles, four interceptions — one returned for a touchdown — and 33 passes defensed in 46 games (33 starts).

Detroit elevated linebacker David Long on Saturday for game day. Long, 28, signed with the practice squad on Tuesday after the Miami Dolphins released him on Nov. 13. He had started six of eight games for the Dolphins this season and had 38 tackles.

In other Lions news, the NFL fined wide receiver Jameson Williams $19,697 for unsportsmanlike conduct for making an obscene gesture during a touchdown celebration in last Sunday’s 52-6 home win over the Jacksonville Jaguars, the NFL Network reported Saturday.

Williams, 23, scored on a 65-yard pass from Jared Goff with 12:55 remaining in the third quarter.